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Malone telegram4/3/2023 The first in-vivo mammalian rat experiments were designed by Dr. He brought over mRNA, constructs, reagents that were developed at the Salk institute by Dr. When he left the Salk Institute, he moved his research over to Vical in 1988. These are available for review and can be found in the link below this statement. His filed patent and disclosures from the Salk included in-vivo RNA transfection, mRNA as a drug, mRNA production, transient gene therapy and also methods for mRNA stabilization. Proceedings of the National Academy of Sciences (PNAS) 86 (16), 6077-6081 This resulted in his seminal paper: Cationic liposome-mediated RNA transfection RW Malone, PL Felgner, IM Verma. There, he pioneered in-vitro RNA transfection and also in-vivo RNA transfection (in frog embryos, as well as mice). It all started when he was at the Salk Institute in 19. He also discovered lipid mediated and naked RNA transfection technologies. Malone is the inventor of mRNA vaccines (and DNA vaccines). His wife writes on their own website, and here we quote at length:ĭr. Jill Malone, all the patents and their history in order to prove his role. Malone himself posted, together with his wife and collaborator, Dr. It was because of these ongoing denials that Dr. Malone’s crucial role in the development of this novel technology. Malone’s name has been removed altogether, but for some footnotes.Įven though this story was reported in July 2021, it seems that there are still people who deny Dr. They completed a number of mRNA vaccination studies that resulted in nine patents on mRNA vaccination with a shared priority date of March 21, 1989.Ī check of the current Wikipedia entry shows that Dr. The first mRNA vaccine experiments were carried out by P. These studies were the first evidence that in vitro transcribed (IVT) mRNA could deliver the genetic information to produce proteins within living cell tissue. demonstrated the idea of nucleic acid-encoded drugs by direct injecting in vitro transcribed (IVT) mRNA or plasmid DNA (pDNA) into the skeletal muscle of mice which expressed the encoded protein in the injected muscle. The term and idea of “RNA as a drug” is first described in this paper. developed a high-efficiency in-vitro and in-vivo RNA transfection system using cationic liposomes, which were used “to directly introduce RNA into whole tissues and embryos”, as well as various cells types. Malone’s crucial involvement in the development of the mRNA technology can be seen in the archived version of his entry from June 14, 2021, which clearly shows his prominent role in the original invention of these mRNA technologies. His research was continued the next year at Vical, and between 19, Malone wrote the patent disclosures for mRNA vaccines.” Robert Malone, M.D., M.S., discovered RNA transfection and, while he was at the Salk Institute in San Diego in 1988, invented mRNA vaccines. LifeSite’s Michael Haynes wrote at the time: “ Dr. Robert Malone, a well-known virologist and immunologist, began to express doubts and objections concerning the current official governmental coronavirus response – including vaccine mandates and vaccination of children – he has come under heavy criticism.Īs LifeSiteNews reported back in July 2021, Malone’s name was removed altogether from the Wikipedia entry of the mRNA vaccine technology, in whose development Dr.
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